Levaquin (generic name Levofloxacin) is a synthetic broad-spectrum antibacterial agent for oral and intravenous administration. Levaquin kills many of the types of bacteria that can infect the lungs, sinuses, skin and urinary tract, and has been shown in a large number of clinical trials to be safe and effective for the treatment of bacterial infections. As with all antimicrobials, inappropriate use of Levaquin may lead to an increase in bacterial resistance to this and other agents.
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The dosage of Levofloxacin is to be adjusted in patients with renal impairment. It is not advised to administer Levofloxacin with antacids containing divalent cations. If antacids is to be administered it should be given 2 hours before or after administration of Levofloxacin. It is recommended to take 2hrs after food. Levofloxacin is to be administered with caution in diabetic patients as it can cause increase or decrease in blood glucose levels. The patient should avoid activities that require alertness during Levofloxacin treatment. The patient should be notified of convulsions and hepatotoxicity during Levofloxacin treatment.
The common side effects reported with Levofloxacin are moniliasis, insomnia, headache, dizziness, dyspnea, nausea, vomiting, constipation, abdominal pain, dyspepsia, rash, pruritis, vaginitis, edema, injection site reaction, chest pain, QT interval prolongation, raised liver enzymes, tendon disorders and rupture.